Botulinum Toxin Treatment In Chennai


Botulinum toxin, the most potent of the neurotoxins produces paralysis by blocking presynaptic release of the neurotransmitter (Acetylcholine) at the neuromuscular junction.


It was developed in 1946 for military use. First patient treated was for squint eye in 1977. It is used for blepahrospam and hemifacial spasm in 1983. J D A Carruthers was the first person to bring Botulinum toxin to aesthetic Medicine.

Why do we use inj Botulinum toxin ?


Cosmetic indications
  • Glabellar lines ( Frown lines)
  • Forehead lines (Expression lines)
  • Lateral canthal lines ( Crow’s feet)
  • Nasalis
  • Upper lip lines
  • Decollete
  • Platysma
General indications
  • Squint eye ( Strabismus)
  • Dystonia
  • Hemifacial spasm and spasticity


Know your facial anatomy.
This is a medical procedure.
Unlike fillers, the action is not immediate.
There is no pain, if done properly.
Technique is critical.
Do not lie flat for 8 hours.
Do not massage the injected area.

Mechanism of action:

  • Botulinum toxin blocks the transmission of the neurotransmitter Acetylcholine across the neuromuscular junction.
  • Nerve endings are not damaged.
  • Temporary effect is due to reversible chemical denervation.
  • Time of onset of action is dose dependent.
  • Production of acetylcholine is not altered.

Treatment with Botulinum toxin:

  • It is a simple procedure; it is safe.
  • It can be repeated.
  • Minimal discomfort with fine needles.
  • NO unwanted side effects if the rules relating to pharmacology and administration are followed.

Contra indications:

  • Pregnancy and lactation
  • Hypersensitivity to Botulinum toxin A and human albumin.
  • Myasthenia gravis
  • Eaton lambert syndrome

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